This trial will test whether two doses of a new drug, brensocatib, can help to prevent pulmonary exacerbations (PEs), which are sudden worsening of symptoms in people with chronic lung disease. COPD is an umbrella term that doctors use to describe chronic bronchitis, emphysema, and chronic asthma. This leads mucus build up in the patient's lungs, making it harder to breathe and creating a viable environment for bacteria and infections. Select your location to view local American Lung Association events and news near you. Read the study Diagnosis. Surgery may be recommended in extreme situations where the bronchiectasis is isolated to a section of lung or there is excessive bleeding. Try to keep the environment around your loved one clean and free of dust and other contaminants that might make their condition worse. Our team has extensive experience diagnosing and treating different types of bronchiectasis and related conditions, including non . The Bronchiectasis treatment focuses on managing symptoms, slowing decline in lung function and preventing exacerbations. . Gravity and force help drain the mucus from your lungs. DelveInsight is a leading Business Consultant, and Market Research firm focused exclusively on life sciences. It comprises NCFBE pipeline drug profiles, including clinical and non-clinical stage products. Your doctor may help you arrange for a home care provider to give you IV antibiotics at home. Smoking affects your lungs and can cause further damage. It covers the pipeline drug profiles, including clinical and nonclinical stage products. This trial will compare two treatments for bronchiectasis not caused by cystic fibrosis: OPEP and HFCWO. (first line treatment: ciprofloxacin 500-750 mg bd for 2 weeks; second line treatment: iv antipseudomonal beta-lactam an . A . Chalmers JD, Chang AB, Chotirmall SH, Dhar R, McShane PJ. A fairly uncommon disease, there are about 139 cases per 100,000 adults in the United States, and it tends to affect women more often than it does men. The new 2018 guideline covers bronchiectasis in adults and provides recommendations and good practice points based on an updated evidence review. Bronchiectasis is a condition where the lung's bronchi become permanently damaged and widened. Oxygen therapy is a treatment that delivers oxygen for you to breathe. To help you and your loved ones have a better understanding of how serious bronchiectasis is in terms of health, wellness, and life expectancy, here . Chronic respiratory disease defined by recurrent bronchial infection and abnormal permanently dilated airways. There are two important . 2021 First Bronchiectasis Trial. Chassagnon G, Brun AL, Bennani S, Chergui N, Freche G, Revel MP. Chinese Medical Association Publishing House Ltd. doi: 10.3760/cma.j.cn112147-20220111-00036. Individual results may vary. New Search; Advanced Search; See Studies by Topic; See Studies on Map . sharing sensitive information, make sure youre on a federal This condition makes you more prone to infection and causes difficulty in breathing. In addition, patients with bronchiectasis have higher hospital costs compared with matched controls [15, 16]. Reviewed and approved by the American Lung Association Scientific and Medical Editorial Review Panel. April 13, 2021 20:20 ET These tests include: The doctor collects a small amount of sputum (spit) to check for any viruses, bacteria or other microorganisms. 2014 Mar;15(4):505-25. doi: 10.1517/14656566.2014.878330. ACB is FET that involves deep breathing exercises. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Join our Parkinsons research for the chance to receive a free genetic test. Though they may be beneficial for some people, they are only used in the most severe situations because they have extreme side-effects. Your doctor may recommend surgery if no other treatments have helped and only one part of your airway is affected. This summary is based on a 2019 summative . In 2021, a series of significant research progress have been made in bronchiectasis, focusing on the mechanism, diagnosis, clinical phenotypes, treatment, comorbidities, etc. Electronic chest clappers or vests are now available to make it easier to perform CPT at home. It supports Pharma companies by providing comprehensive end-to-end solutions to improve their performance. This trial is testing a new drug to treat MAC lung infection in people with bronchiectasis. MRI facility. Martnez-Garca M, Oscullo G, Garca-Ortega A, Matera MG, Rogliani P, Cazzola M. Drugs. Goyal V, Grimwood K, Marchant J, Masters IB, Chang AB. The doctor may decide to perform some imaging tests such as X rays, CT or CAT scans to assess the anatomy of the lung and look for visible damages or thickening in the airways. Bronchiectasis is a chronic lung disease characterised by inflammation of the airways, mucociliary dysfunction, mucus plugging, and progressive structural damage. This chronic, progressive respiratory disorder can cause persistent coughing and repeated infections. The trial will last 28 days, and participants will be randomly assigned to either take ARINA-1 or a placebo twice daily. Scenario: COVID-19: Covers management when considering the possibility of COVID-19. Unauthorized use of these marks is strictly prohibited. Symptoms of bronchiectasis are often present for many . While most patients with bronchiectasis have chronic symptoms, a particularly severe episode is called an exacerbation. Treatment for bronchiectasis is designed to prevent lung infections and reduce or prevent exacerbations (flareups). This trial is testing a new medication to see if it helps people with bronchiectasis. Bronchiectasis. Inhaled Therapy Gets Breakthrough Designation for Non-Cystic Fibrosis Bronchiectasis. You may experience side effects from this treatment, such as a dry or bloody nose, tiredness, and morning headaches. The growing body of patients attending the bronchiectasis clinic has also permitted extensive research into new and improved treatments for bronchiectasis. Scenario: Suspected bronchiectasis: Covers the management of suspected bronchiectasis. Several studies have shown that many mediators are involved in the pathogenesis of bronchiectasis, such as lipids, platelets, and respiratory microorganisms, providing new insights into the development of prevention and therapy targets of bronchiectasis. Please enable it to take advantage of the complete set of features! Share sensitive information only on official, secure websites. Join over 700,000 people who receive the latest news about lung health, including COVID-19, research, air quality, inspiring stories and resources. 3 The implications of this guidance for primary care . Talk to our experts at the American Lung Association Lung HelpLine and Tobacco QuitLine. Epidemiological characteristics of nontuberculous mycobacteriosis and bronchiectasis: comparative study using national mortality statistics from 1970 to 2015 in Japan. Because bronchiectasis remains an underdeveloped area of respiratory careunlike COPD or cystic fibrosismost patients are unfamiliar with its causes, symptoms, and effective treatment methods. All readers/viewers of this content are advised to consult their doctors or qualified health professionals regarding specific health questions. Antibiotics are the main treatment for the repeated lung infections that bronchiectasis causes. (2021). Secure .gov websites use HTTPS https://bit.ly/2WPfVZ7. A clinical trial for an investigational respiratory syncytial virus (RSV) vaccine combined with an approved flu vaccine for older adults. Chronic obstructive lung disease (COPD) is a lung condition that makes breathing difficult and that is currently incurable. Our service is free and we are here to help you. To ensure these treatments achieve success in randomised clinical trials-and therefore reach patients-we propose a reassessment of the current approach to bronchiectasis. ARINA-1 . Los Angeles, USA, April 13, 2021 (GLOBE NEWSWIRE) -- Non-cystic Fibrosis Bronchiectasis Treatment 2021 | Prominent Players, Pipeline Growth, Future Trends, Unmet Demands, Emerging Therapies . New and Current Treatments for COPD Medically reviewed by Adithya Cattamanchi, M.D. Tiew PY, et al. New therapeutic options for Non-cystic Fibrosis Bronchiectasis treatment as 5+ companies are working for the drug profiles.Los Angeles, USA, April 13, 2021 (GLOBE NEWSWIRE) -- Non-cystic Fibrosis . . Bronchiectasis is a long-term condition with symptoms that need to be managed over many years. Promising progress in new treatment for bronchiectasis sufferers, For people with bronchiectasis, the symptoms and exacerbations of the disease can have a debilitating impact on their quality of life. The trial will last for 52 weeks, and patients who complete the trial will be eligible for an extension where they will receive the drug for at least one more year. The Nontuberculous Mycobacteria (NTM) Australia Research Network is brought Greenslopes Private Hospital, Newdegate Street, Greenslopes QLD 4120, Studies Seeking Recruitment: Clinical Trials, Studies Seeking Recruitment: Veteran Health. The condition makes the airways permanently broadened and inflamed. (COPD). Bronchiectasis is a lung condition that occurs when the bronchial tubes of your lungs are enlarged permanently. While more research and clinical trials are needed, the top-line results of this study highlight the tremendous value of clinical trials in providing patients with access to more effective, simpler treatments. These may be accompanied by pleuritic . The risk of developing bronchiectasis increases with age. This chronic, progressive respiratory disorder can cause persistent coughing and repeated infections. Epub 2020 Nov 26. Bronchiectasis is an irreversible widening (dilation) of portions of the breathing tubes or airways (bronchi) resulting from damage to the airway wall. These data are in agreement with other recent publications that have also demonstrated the great economic burden related to bronchiectasis. Bronchiectasis often is treated with medicines, hydration, and chest physical therapy (CPT). Australian adults with bronchiectasis: The first report from the Australian Bronchiectasis Registry, Updated British Thoracic Society guidelines, Updated Spanish guidelines on the treatment of bronchiectasis in adults, New Antibiotic Formulation Better at Controlling Infections in Bronchiectasis, New Guidelines on Managing Adult Bronchiectasis. Thank you for your interest in spreading the word on European Respiratory Society . Guidelines Summary. Some of the most common causes of bronchiectasis are: Lung infections can cause severe damage to the walls of the airways, leading to bronchiectasis. and we update our articles when new . JAMA. Background Neutrophilic inflammation in the airway is a hallmark of bronchiectasis. Bronchiectasis: moving from an orphan disease to an unpleasant socioeconomic burden, Human Regulatory. However, in recent years, bronchiectasis has no longer been considered an orphan disease [2]. Clipboard, Search History, and several other advanced features are temporarily unavailable. , Pulmonology By Valencia Higuera Updated on Oct 4, 2021 Current treatments This site needs JavaScript to work properly. Oxygen therapy may be recommended to raise low blood oxygen levels. Sievert, CE et al. Want updates on the latest lung health news, including COVID-19, research, inspiring stories and health information? Print 2018 Sep. Respirology. As expected, this large number of patients awakened the recognition of an unmet need for effective therapeutic interventions for the management of bronchiectasis. HHS Vulnerability Disclosure, Help It is interesting to note that, as found by Phua et al. A doctor or technician may take a sputum sample from expectoration (coughing), use a tube to suction some of the sputum out, or they may induce coughing and sputum production with a saline solution. The trial will last for 52 weeks, and patients who complete the trial will be eligible for an extension where they will receive the drug for at least . For further information, refer to the detailed report @ NCFBE Pipeline Therapeutics, Scope of Non-cystic Fibrosis Bronchiectasis Pipeline Drug Insight, Key Questions regarding Current Non-cystic Fibrosis Bronchiectasis Treatment Landscape and Emerging Therapies Answered in the Pipeline Report, Get a customised pipeline report @ Non-cystic Fibrosis Bronchiectasis Drugs Pipeline Report. This trial will study the effects of Trikafta on non-cystic fibrosis bronchiectasis sufferers, measuring clinical endpoints, quality of life and weight, plus collecting biopsy material to test cellular response. official website and that any information you provide is encrypted Careers. Eur Respir J. Airway Clearance Devices: Some patients exhale into a hand-held device to help break up mucus. The trial will last 28 days, and participants will be randomly assigned to either take ARINA-1 or a placebo twice daily. DPP1 is an enzyme held to activate neutrophil serine proteases (NSPs), such as neutrophil elastase, in neutrophils when formed in the bone marrow. Accessibility What are the current novel therapies, targets, mechanisms of action, and technologies developed to overcome the limitation of existing NCFBE therapies? DelveInsight' s Adult T-Cell Leukemia-Lymphoma Market Insights, Epidemiology and Market Forecast - 2030 report provides a detailed overview of the disease and a depth understanding of historical and forecasted epidemiology. Research to be conducted at TBRHSC Cardio & Res. It also includes the NCFBE therapeutics assessment by product type, stage, route of administration, and molecule type and further highlights the inactive Non-cystic Fibrosis Bronchiectasis pipeline products. Until a few decades ago, bronchiectasis was considered an . PMC Take antibiotics for one to two weeks during flare-ups. You can search for clinical trials on the Lung Association's Clinical Trial Registry or ClinicalTrials.gov. Obesity, Nutrition, and Physical Activity, Treat any underlying conditions and lung infections, Remove mucus (a slimy substance) from your lungs, An electric chest clapper, known as a mechanical percussor, An inflatable therapy vest that uses high-frequency air waves to force mucus toward your upper airways so you can cough it up, A small handheld device that you breathe out through, which causes vibrations that dislodge the mucus, A mask that creates vibrations to help break loose mucus from your airway walls. . "It is increasingly recognized that patients with COPD have different phenotypes, and treatment can be . [14] have comprehensively evaluated the prevalence and incidence of bronchiectasis requiring hospitalisation in Singapore, as well as the associated healthcare utilisation and costs. The majority of this cost was due to hospitalisation, representing 55.8% of direct medical costs. European Respiratory Society442 Glossop RoadSheffield S10 2PXUnited KingdomTel: +44 114 2672860Email: journals@ersnet.org, Copyright 2023 by the European Respiratory Society, Diviso de Pneumologia, Instituto do Corao (InCor), Hospital das Clinicas (HCFMUSP), Faculdade de Medicina, Universidade de So Paulo, So Paulo, Brazil. eCollection 2023 Jan. Liu Y, Du L, Zhu Y, Liu X, Zhou N, Li C, Li Q, He P. Acta Biochim Biophys Sin (Shanghai). Receive premium care & cutting edge treatments by enrolling in bronchiectasis clinical trials today. Find a Doctor Find a Doctor. Bethesda, MD 20894, Web Policies The British Thoracic Society (BTS) guideline for non-cystic fibrosis bronchiectasis, covering adults and children, was published in 2010 and updated in 2013. Session 4: New treatments. DelveInsight Business Research LLP April 13, 2021 20:20 ET | Source: DelveInsight Business Research LLP European Respiratory Society guidelines for the management of adult bronchiectasis. 2018 Feb 7;2(2):CD012528. Maintain a healthy diet, low in sodium, added sugars, saturated fats and refined grains. Uses, Side Effects, & Dosage, What is Incruse Ellipta? Accessibility The drug is sent for clinical trials by Xellia Pharmaceuticals, Zambons long-standing partner, with which it shares the objective of coming of this formulation to NCFBE patients globally. This trial is testing a new medication for bronchiectasis called ARINA-1. Federal government websites often end in .gov or .mil. Data from 589 , Bronchiectasis is a chronic respiratory disease of airway dilatation, where patients typically suffer from respiratory infections, fatigue, sputum, cough, dyspnoea and poor quality of life , The Australian Bronchiectasis Registry (ABR), established in 2015, aims to evaluate clinical phenotypes of Australians with bronchiectasis. Here you can find out all about the day and watch the recordings of the sessions: Session 1: Basics of bronchiectasis. Mucus Thinning Medication may be prescribed to help bronchiectasis patients cough up mucus. 10 Bronchiectasis Clinical Trials Near Me, Top Hospitals for Bronchiectasis Clinical Trials, University of Texas Health Science Center at Tyler, Cardiopulmonary rehabilitation post lung transplant, Top Cities for Bronchiectasis Clinical Trials, Bronchiectasis Clinical Trials by Phase of Trial, Bronchiectasis Clinical Trials by Age Group, Most Recent Bronchiectasis Clinical Trials, Top Treatments for Bronchiectasis Clinical Trials, Idiopathic Pulmonary Fibrosis Clinical Trials 2023, Interstitial Lung Disease Clinical Trials 2023, The Ultimate Guide to Understanding Cystic Fibrosis, A Guide To 7 Of The Most Common Genetic Disorder, What is Spiriva? Macrolides are a specific type of antibiotics that not only kill certain types of bacteria but also reduce inflammation in the bronchi. This content is for informational and educational purposes only. Bronchiectasis is a chronic condition in which irreversible damage to and dilation of the bronchi lead to symptoms of persistent or recurrent bronchial sepsis. Nat Med 2021; 27:688. Bronchiectasis has received increasing attention in recent years. You will now receive email updates from the American Lung Association. Antibiotics by inhalation have high drug concentrations in the airways, minimising systemic exposure and potential side effects. MeSH Interventions for bronchiectasis: an overview of Cochrane systematic reviews. Your doctor may prescribe expectorants and mucus thinners to help you cough up mucus. 2017 Sep 9;50(3):1700629. doi: 10.1183/13993003.00629-2017. Colistimethate sodium is one of the antibiotics against Pseudomonas aeruginosa infections, and the I-Neb AAD system is an inhalation system developed to confer nebulised medications into the lung. Another important aspect related to bronchiectasis expenses is that the greater the severity of the disease, the higher its healthcare costs. All Rights Reserved. Bronchiectasis clinical trials are ongoing in the United States and around the world, with a variety of treatments being tested. Orphan Designation: Overview, Bronchiectasis in Germany: a population-based estimation of disease prevalence, Prevalence and incidence of bronchiectasis in Catalonia, Spain: a population-based study, Prevalence and incidence of noncystic fibrosis bronchiectasis among US adults in 2013, European Respiratory Society guidelines for the management of adult bronchiectasis, Brazilian consensus on non-cystic fibrosis bronchiectasis, Spanish guidelines on treatment of bronchiectasis in adults, Bronchiectasis: new therapies and new perspectives, Current and future pharmacotherapy options for non-cystic fibrosis bronchiectasis, Epidemiology and economic burden of bronchiectasis requiring hospitalisation in Singapore, Economic burden of non-cystic fibrosis bronchiectasis in the first year after diagnosis from a US health plan perspective, Economic burden of bronchiectasis in Germany, Cost of hospitalizations due to exacerbation in patients with non-cystic fibrosis bronchiectasis, Bronchiectasis-associated hospitalizations in Germany, 20052011: a population-based study of disease burden and trends, Time trends in hospital admissions for bronchiectasis: analysis of the Spanish national hospital discharge data (2004 to 2013), Trends and burden of bronchiectasis-associated hospitalizations in the United States, 19932006, A prospective cohort study of the use of domiciliary intravenous antibiotics in bronchiectasis, Latin America validation of FACED score in patients with bronchiectasis: an analysis of six cohorts, Dyspnoea in COVID-19 recovery beyond the ICU, ORCID record for Rodrigo Abensur Athanazio, http://creativecommons.org/licenses/by-nc/4.0/, www.ema.europa.eu/en/human-regulatory/overview/orphan-designation-overview. BMC Pulm Med. Bronchiectasis. A rare coincidence of Turner syndrome and bronchiectasis: A case report. Doing this helps loosen the mucus from your lungs so you can cough it up. Colistimethate sodium is a polymixin antibiotic and bactericidal against susceptible Gram-negative bacteria. Good hydration helps keep airway mucus moist and slippery and easier to cough up. Your doctor may prescribe other medicines, depending on your symptoms or other conditions you may have. In fact, it reinforces the great economic impact of this condition, since health-related expenses with bronchiectasis should be even higher. CHF 6333 is a medicinal product for treating Cystic Fibrosis and Non-cystic Fibrosis Bronchiectasis and undergoing clinical testing. Some patients may be eligible for Clinical Trials. HomeClinical TrialsA Guide to Bronchiectasis and Clinical Trials. However, we are still seeing only the tip of the iceberg and we have a long road to walk before identifying the appropriate safe and cost-effective interventions for bronchiectasis management. 2022 Nov 1;22(1):394. doi: 10.1186/s12890-022-02198-2. Uses, Side Effects, & Dosage. Acta Biochim Biophys Sin (Shanghai). Scenario: Infective exacerbation: Covers the management of an infective exacerbation of bronchiectasis. Bookshelf 2017. In a . Azithromycin was associated with a decreased pulmonary exacerbation rate but increased macrolide resistance. 77 References. I also am taking Bisoprolol Fumarate 2.5 mg (a beta blocker) for heart issues. The bronchi dilate, usually . sharing sensitive information, make sure youre on a federal A team of world recognised experts in bronchiectasis have contributed to this monograph, covering topics , The 3rd World Bronchiectasis conference was held in July 2018 in Georgetown, Washington DC. Integrative microbiomics in bronchiectasis exacerbations. This version is distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0. Bronchiectasis is growing in prevalence and there are limited treatment options available. It is logical to expect that this equation of greater recognition of bronchiectasis cases plus high daily therapeutic load necessity plus high number of exacerbations, including the need for hospitalisation for long periods, would result in a high expenditure of health-related resources. This website uses cookies to improve content delivery. Neutrophils are the most common type of white blood cell and execute a vital role in pathogen destruction and inflammatory mediation. 2023 Feb 20;9(1):00424-2022. doi: 10.1183/23120541.00424-2022. There are two types of COPD, one caused by chronic bronchitis and the other caused by emphysema. 2018 Oct;74(5):299-314. doi: 10.1016/j.pneumo.2018.09.009. In this study by Phua et al. It can be fatal. Live Chat with us, Monday through Friday, 8:30 a.m. to 5:00 p.m. EST. In recent years, we have experienced an exponential increase in studies focused on unravelling the pathophysiology of bronchiectasis, on testing different therapeutic interventions and on evaluating its socioeconomic burden. This finding reinforces the importance of early recognition of this disease. If you are feeling overwhelmed, talk to someone. FOIA Surgery may be recommended in extreme situations where the bronchiectasis is isolated to a section of lung or there . New frontiers in the treatment of COPD. When health care providers suspect bronchiectasis, they might order blood tests to check if there are any underlying conditions such as rheumatoid arthritis and Crohns disease present. I changed doctors about 3 years ago and continued the antibiotic treatment until tests showed negative for a year . The airways normally produce a small amount of mucus (sputum or phlegm) which traps any germs that enter the lungs. No treatments have been licensed by regulatory agencies worldwide, and most therapies used in clinical practice are based on very little evidence. . This is a relevant topic since not every finding can be promptly extrapolated to the reality of other populations. The authors found that the annual direct medical cost associated with bronchiectasis was USD 9.6 million in 2017. Avoid strong smells and lung irritants such as dust, smoke, and fumes. This trial will test a new device that monitors heart rate, breathing rate, temperature, cough, and activity to see if it can predict worsening or increasing severity of lung conditions. The overlap between bronchiectasis and chronic airway diseases: state of the art and future directions. This is the 3rd cardiac med that has been prescribed in hopes of . 2022 Sep;82(14):1453-1468. doi: 10.1007/s40265-022-01785-1. CPT is also known as physiotherapy, chest clapping, and percussion. Unable to load your collection due to an error, Unable to load your delegates due to an error. Bronchiectasis in adults is a chronic disorder associated with poor quality of life and frequent exacerbations in many patients. A Respiratory Syncytial Virus (RSV) vaccine clinical trial for older adults. With acquired, or environmental bronchiectasis, damages to the airways can begin during childhood; however, a person might not develop any symptoms until many years later. Non-cystic Fibrosis Bronchiectasis Pipeline Report, Bone Distractors/Distraction Osteogenesis Devices Market. Bronchiectasis is a common comorbid condition in patients with COPD, for which long-term azithromycin is effective in preventing exacerbation. Open AccessPublished:August 05, 2021DOI:https://doi.org/10.1016/j.lanwpc.2021.100239 Aboriginal children have higher rates of , Free training module for paediatric respiratory disease Chronic respiratory disease is prevalent among Aboriginal children but most doctors never had the opportunity to learn about , Bronchiectasis among Australian Aboriginal and non-Aboriginal patients in the regional and remote population of the Northern Territory of Australia Purpose:Chronic respiratory disorders are highly prevalent , Neutrophil extracellular traps, disease severity, and antibiotic response in bronchiectasis: an international, observational, multicohort study This research identifies, for the first time, neutrophil extracellular trap , Improving Aboriginal Childrens Lung Health developed by the Research Education and Training program in Western Australia, is an electronic training module, endorsed by RACGP, , A novel anti-inflammatory treatment for bronchiectasis that targets neutrophils has shown promising results in a phase 2 trial. 8600 Rockville Pike et al. COPD is an umbrella term for a collection of conditions causing lung damage, including chronic bronchitis and emphysema, and affects around three million people in the UK. There is an urgent need for new treatments and these trial results represent a significant step forward in addressing this problem. The European Respiratory Society guidelines for the management of adult bronchiectasis describe the appropriate investigation and treatment strategies determined by a systematic review of the literature. 212-305-5730. 2019 Mar;24(3):227-237. doi: 10.1111/resp.13459. doi: 10.1002/ccr3.6378. Introduction. Patients in the WILLOW Trial have shown significant reductions in both the duration and severity of pulmonary exacerbations (increases in severity of disease symptoms). Several clinical trials and guidelines have been published, with the aim of improving quality of life, reducing the number of infectious pulmonary exacerbations, and delaying disease progression [810]. Drinking plenty of fluid, especially water, helps prevent airway mucus from becoming thick and sticky. Clinical Trial Guide for Seniors and the Elderly, Clinical Trial Guide for Parents and Children, Guide To Keeping Your Health Records Secure, Clinical Trials on the Effects of Bullying, Clinical Trials on the Positive Effects of Gardening and Experiencing Nature, Clinical Trials on the Disaster Mental Health, A Guide to Bronchiectasis and Clinical Trials, https://www.bmj.com/rapid-response/2011/11/01/role-pneumococcal-and-influenza-vaccination-management-bronchiectasis, https://www.nhlbi.nih.gov/health-topics/bronchiectasis, https://www.lung.org/lung-health-and-diseases/lung-disease-lookup/bronchiectasis/diagnosing-and-treating.html.
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