Therapeutic Research Faculty 2020. Paeoniflorin: an antihyperlipidemic agent from Paeonia lactiflora. Eur Neurol 1992;32(1):44-51. Gallacher SD, Tsokolas G, Dimitropoulos I. Liquorice-induced apparent mineralocorticoid excess presenting in the emergency department. Eriksson JW, Carlberg B, Hillom V. Life-threatening ventricular tachycardia due to liquorice-induced hypokalemia. View abstract. 2014 Jan;35(1):87-99. View abstract. View abstract. Side effects, toxicity, and interactions. J Endocrinol Invest 2003;26:646-50. Arch Pharm Res 2003;26(10):832-839. Licorice-induced hypermineralocorticoidism. View abstract. View abstract. Mol Cell Endocrinol. Steroids 2004;69(11-12):763-766. Celery juice has become very popular now as it is believed to cure many health problems including obesity, thyroid, gout, blood pressure and fluid retention. If you take birth control pills along with peony, use an additional form of birth control such as a condom. 2013 Sep;117(3):614-21. View abstract. But the potential side effects are real enough. Some medications are moved in and out of cells by pumps. Riv Patol Nerv Ment 1983;104(4):179-183. View abstract. Lethal liquorice lollies (liquorice abuse causing pseudohyperaldosteronism). J Am Coll.Nutr 2007;26(3):209-218. Kang, D. G., Moon, M. K., Choi, D. H., Lee, J. K., Kwon, T. O., and Lee, H. S. Vasodilatory and anti-inflammatory effects of the 1,2,3,4,6-penta-O-galloyl-beta-D-glucose (PGG) via a nitric oxide-cGMP pathway. Hajiaghamohammadi AA, Zargar A, Oveisi S, Samimi R, Reisian S. To evaluate of the effect of adding licorice to the standard treatment regimen of Helicobacter pylori. Antiviral Res 1987;7(2):99-107. It shows a wide range of biological and pharmacological activities, including anti-inflammatory and immune regulatory actions. View abstract. 2003;84(1):85-89. [Treatment of refractory polycystic ovary syndrome by bushen huoxue method combined with ultrasound-guided follicle aspiration]. Drugs & Vitamins . View abstract. Ohta H, Ni JW, Matsumoto K, et al. The herb has also been studied for use in canine atopic dermatitis along with white peony (Paeonia lactiflora) and licorice (Glycyrrhiza glabra). Yoon JY, Cha JM, Hong SS, et al. View abstract. Z Kardiol 1991;80(6):389-391. Sigurjonsdottir HA, Ragnarsson J, Franzson L, Sigurdsson G. Is blood pressure commonly raised by moderate consumption of liquorice? View abstract. Tu, J. H., He, Y. J., Chen, Y., Fan, L., Zhang, W., Tan, Z. R., Huang, Y. F., Guo, D., Hu, D. L., Wang, D., and Hong-Hao Zhou. View abstract. $9.44 $ 9. ""- . Information from this source is evidence-based and objective, and without commercial influence. Cancer Lett. There are studies with assisted nutrients to expedite healing and mitigate side effects of hormone imbalances associated with IVF/IUI discussed below. 83rd Annual Meeting of the Endocrine Society, June 20-23 2001;abstract P1-573. Indian J Med Res 1993;98:69-74. Hukkanen J, Ukkola O, Savolainen MJ. When eaten in large quantities, black licorice can cause serious health issues. He X, Xing D, Ding Y, et al. Awad N, Makar G, Burroughs V, Ravi P, Burroughs SR. Licorice-induced apparent mineralocorticoid excess causing persistent hypertension and hypokalemia. Zhang YD, Lorenzo B, Reidenberg MM. J Clin Endocrinol Metab 2003;88:2384-92. Effects of total glucosides of peony on immunological hepatic fibrosis in rats. Br J Clin Pract 1972;26(12):563-566. Antiviral Res 1987;7(3):127-137. J Hepatol 1994;21:601-9. View abstract. Side effects of peony tea! View abstract. It may disrupt the production of sex hormones ( 9 ). Corse, F. M., Galgani, S., Gasparini, C., Giacanelli, M., and Piazza, G. Acute hypokalemic myopathy due to chronic licorice ingestion: report of a case. View abstract. Guo TL, Zhou XW. Ital J Neurol Sci 1983;4(4):493-497. Immediately afterwards, Teacher Liu looked at her, picked up her paper, and said, Student Zhou Xiaotong, this time I ll give you a warning. Yang F, Qi X, Du Y, et al. Med Princ Pract 2010;19(6):485-489. Da Nagao, Y., Sata, M., Suzuki, H., Tanikawa, K., Itoh, K., and Kameyama, T. Effectiveness of glycyrrhizin for oral lichen planus in patients with chronic HCV infection. Kent UM, Aviram M, Rosenblat M, Hollenberg PF. Arentz S, Smith CA, Abbott J, Fahey P, Cheema BS, Bensoussan A. Monograph. View abstract. Muscle cramps.Early research suggests that taking a specific combination of peony and licorice (Shakuyaku-kanzoh-to) might ease muscle cramps in people with liver cirrhosis and in people undergoing hemodialysis. Severe hypokalemic paralysis and rhabdomyolysis due to ingestion of liquorice. Arch Pharm Res 2002;25(3):293-299. Morris DJ, Davis E, Latif SA. CJEM 2009;11(1):94-96. Chamberlain, J. J. and Abolnik, I. Postgrad Med J 1980;56(657):526-529. Loop diuretics can also decrease potassium levels. Nat Prod Res 2007;21(14):1234-1241. CJEM 2010;12(3):224-225. 2020;2020:8401239. 2017 Apr 1;27(2):150-154. doi: 10.1684/ejd.2016.2946. View abstract. View abstract. A man in Massachusetts died after eating too much black licorice, which contains a compound known to be toxic in large doses, according to a new report. J Assoc Physicians India 1978;26(9):811-814. J Infect.Chemother. But, she survived . 2016 Nov;48(11):1873-1880. doi: 10.1007/s11255-016-1345-5. A dose of 800 milligrams (mg) or more of licorice root per day has been linked to low potassium levels. Hinoshita F, Ogura Y, Suzuki Y, et al. 1979;14(5):605-607. Antimicrobial isoflavanoids and related substances from Glycyrrhiza glabra L. var. Engqvist, A., von Feilitzen, F., Pyk, E., and Reichard, H. Double-blind trial of deglycyrrhizinated liquorice in gastric ulcer. Hawrelak, J. Side-effects of low-potassium levels can include lethargy and abnormal heart rhythms. A systemic review and meta-analysis of the clinical efficacy and safety of total glucosides of peony combined with methotrexate in rheumatoid arthritis. Licorice has been used as a medicinal plant from 2.500 years. Era of Hope Mtg, Dept Defense; Breast Cancer Res Prog, Atlanta, GA 2000;Jun 8-11. A multicentre trial. Braz J Infect Dis 2016;20(6):534-8. [RETRACTED]. Melzer J, Rosch W, Reichling J, et al. View abstract. A controlled trial of traditional Chinese medicinal plants in widespread non-exudative atopic eczema. Acta Endocrinol (Buchar) 2020;16(4):508-510. Thom E and Wollan T. A controlled clinical study of kanjang mixture in the treatment of uncomplicated upper respiratory tract infections. View abstract. View abstract. Mamgain RK, Gupta M, Mamgain P, et al. Phytother Res 2012;26(9):1381-1384. Back to the Blog. Feng Z, Xu J, He G, et al. Although white peony is generally considered safe for most people, drinking large amounts might have some negative consequences. This Halloween, you'll want to stay vigilant about the candy . NOW Supplements, Licorice Root (Glycyrrhiza glabra) 450 mg, Herbal Supplement, 100 Veg Capsules 208. J Dermatolog Treat 2003;14(3):153-157. Some of these health benefits have also . Acharya SK, Dasarathy S, Tandon A, et al. We could use compounds in these foods to . Mu Y, Zhang J, Zhang S, et al. The sweet cake that reaches parts other cakes can't! Some medications are changed and broken down by the liver. View abstract. Foster CA, Church KS, Poddar M, Van Uum SH, Spaic T. Licorice-induced hypertension: a case of pseudohyperaldosteronism due to jelly bean ingestion. View abstract. Int Immunopharmacol. View abstract. It has an effect similar to aldosterone. Am J Med Sci 2003;325:153-6. Effect of Shakuyaku-kanzo-to (Tsumura TJ-68) on muscle cramps accompanying cirrhosis in a placebo-controlled double-blind parallel study. Steinberg, D., Sgan-Cohen, H. D., Stabholz, A., Pizanty, S., Segal, R., and Sela, M. N. The anticariogenic activity of glycyrrhizin: preliminary clinical trials. View abstract. Lancet 2000;355(9198):134-138. Phytother Res. View abstract. Rikknen K, Seckl JR, Heinonen K, Pyhl R, Feldt K, Jones A, Pesonen AK, Phillips DI, Lahti J, Jrvenp AL, Eriksson JG, Matthews KA, Strandberg TE, Kajantie E. Maternal prenatal licorice consumption alters hypothalamic-pituitary-adrenocortical axis function in children. The effect of Glycyrrhiza glabra L. on primary dysmenorrhea compared with ibuprofen: A randomized, triple-blind controlled trial. Evid Based Complement Alternat Med 2016;2016:8292486. Taking licorice and loop diuretics together might make potassium levels drop too low. Biofactors 2009;35(1):98-104. 2004;24(12):1084-1086. Am J Epidemiol 2002;156:803-5.. View abstract. 2000;19(8):434-439. Previous studies have estimated that a dose of 1 to 5 grams (g) of licorice root daily is safe for most adults. The dose of your warfarin might need to be changed. Nasal irrigation with Glycyrrhiza glabra extract for treatment of allergic rhinitis - A study of in vitro, in vivo and clinical trial. Effect of shakuyaku-kanzoh-toh, a prescription composed of shakuyaku (Paeoniae Radix) and kanzoh (Glycyrrhizae Radix) on guinea pig ileum. Warfarin is used to slow blood clotting. Liquorice-induced rise in blood pressure: a linear dose-response relationship. Peony might block chemicals that can cause pain and swelling . Estrogenic activity of herbs commonly used as remedies for menopausal symptoms. View abstract. View abstract. View abstract. View abstract. View abstract. Goto, F., Asama, Y., and Ogawa, K. Sho-saiko-to-ka-kikyo-sekko as an alternative treatment for chronic tonsillitis to avoid surgery. Phytother Res. View abstract. O'Connell K, Kinsella J, McMahon C, Holian J, O'Riordan S. Posterior reversible encephalopathy syndrome (PRES) associated with liquorice consumption. Medically reviewed by Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT By Kirsten Nunez on October 16, 2020. Cooper, H., Bhattacharya, B., Verma, V., McCulloch, A. J., Smellie, W. S., and Heald, A. H. Liquorice and soy sauce, a life-saving concoction in a patient with Addison's disease. Pontefract cakes can be bad for you: refractory hypertension and liquorice excess. View abstract. Kroes, B. H., Beukelman, C. J., van den Berg, A. J., Wolbink, G. J., van Dijk, H., and Labadie, R. P. Inhibition of human complement by beta-glycyrrhetinic acid. Phytother.Res. Janse A, van Iersel M, Hoefnagels WH, Olde Rikker MG. View abstract. View abstract. Zangooei Pourfard M, Mirmoosavi SJ, Beiraghi Toosi M, et al. Clinical and immunological consequences of total glucosides of paeony treatment in Sjgren's syndrome: A randomized controlled pilot trial. View abstract. Adjuvant role of a new emollient cream in patients with palmar and/or plantar psoriasis: a pilot randomized open-label study. Botanical names: Paeonia lactiflora, Paeonia suffruticosa, Paeonia veitchii How It Works Peony contains a unique glycoside called paeoniflorin. View abstract. J Hum Hypertens 2003;17(2):125-131. A. and Cunliffe, W. J. Self-medication with liquorice in a patient with Addison's disease. 2004;4(3):377-386. View abstract. Jafari Z, Emtiazy M, Sohrabvand F, et al. Low doses of liquorice can induce hypertension encephalopathy. Doeker, B. M. and Andler, W. Liquorice, growth retardation and Addison's disease. Licorice root contains glycyrrhizin, which can cause side effects when eaten in large amounts. 2014 Jun;20(6):516-20. People who regularly take large amounts of licorice, more than 20 g/day, may raise blood levels of the hormone aldosterone, which can cause serious side effects, including headache, high blood pressure, and heart problems. Luchon, L., Meyrier, A., and Paillard, F. [Hypokalemia without arterial hypertension by licorice poisoning]. Antiviral Res 2003;59(1):41-47. Other conditions. N Engl J Med 1999;341:1158. View abstract. Zhong.Xi.Yi.Jie.He.Za Zhi. Here are a few of them: . Hyodo T, Taira T, Kumakura M, et al. Brush, J., Mendenhall, E., Guggenheim, A., Chan, T., Connelly, E., Soumyanath, A., Buresh, R., Barrett, R., and Zwickey, H. The effect of Echinacea purpurea, Astragalus membranaceus and Glycyrrhiza glabra on CD69 expression and immune cell activation in humans. J Pharm Pharmacol 2003;55:1275-82. Westman EC, Guthrie GP. View abstract. View abstract. Lancet 1990;335(8697):1060-3. Balakrishnan, V., Pillai, M. V., Raveendran, P. M., and Nair, C. S. Deglycyrrhizinated liquorice in the treatment of chronic duodenal ulcer. Teelucksingh S, Mackie AD, Burt D, McIntyre MA, Brett L, Edwards CR. Researchers from the University of Minnesota studied 50 atopic dogs in a randomized, double-blind, placebo-controlled trial. An unusual cause of hypokalemic paralysis: chronic licorice ingestion. Yuan, H. N., Wang, C. Y., Sze, C. W., Tong, Y., Tan, Q. R., Feng, X. J., Liu, R. M., Zhang, J. Yorgun, H., Aksoy, H., Sendur, M. A., Ates, A. H., Kaya, E. B., Aytemir, K., and Oto, A. Brugada syndrome with aborted sudden cardiac death related to liquorice-induced hypokalemia. Early evidence suggests that taking 45 grams of a specific product containing peony and licorice (Peony-Glycyrrhiza Decoction, PGD) daily for 4 weeks reduces levels of a hormone called prolactin in women with high levels of prolactin, without affecting other hormone levels or mental symptoms. After lab testing, the Cheng team found that Huang Qin Tang had a high inhibitory property against the debilitating side effects of a chemotherapy drug called CPT-11 (later approved as irinotecan), including diarrhea, nausea, and vomiting. Holtmann G, Madisch A, Juergen H, et al. Licorice is believed to have anti-androgenic effects, meaning that it may be active to reduce testosterone levels. J Clin Psychopharmacol 2008;28(3):264-370. View abstract. Phytother.Res 2004;18(3):241-243. Oral Dis 2012;18(1):32-39. Sakamoto, S., Yoshino, H., Shirahata, Y., Shimodairo, K., and Okamoto, R. Pharmacotherapeutic effects of kuei-chih-fu-ling-wan (keishi-bukuryo-gan) on human uterine myomas. Licorice can decrease how quickly the body breaks down corticosteroids. View abstract. Lee, S., Lim, J. M., Jin, M. H., Park, H. K., Lee, E. J., Kang, S., Kim, Y. S., and Cho, W. G. Partially purified paeoniflorin exerts protective effects on UV-induced DNA damage and reduces facial wrinkles in human skin. Licorice is Sita (cold) in nature, Guru (heavy) to digest, and Madhura (sweet) in . View abstract. The sweet stuff in your kids' trick-or-treat buckets may come with a bitter side effect. View abstract. Peony and Licorice is a safe and gentle yet powerful formula that is famous for its ability to build blood and balance menstrual cycles. View abstract. Pulmonary edema following a licorice binge. Ou TT, Wu CH, Hsu JD, et al. View abstract. Anti Erection Pill. Deng, Y. Y., Chen, Y. P., Wang, L., Hu, Z., Jin, Y., Shen, L., Zhu, R., and Zhong, Y. J Peripher.Nerv.Syst. Pharmazie 2010;65(8):624-8. View abstract. Int Urol Nephrol. Cumming, A. M., Boddy, K., Brown, J. J., Fraser, R., Lever, A. F., Padfield, P. L., and Robertson, J. I. View abstract. Effects of mouthwash interventions on xerostomia and unstimulated whole saliva flow rate among hemodialysis patients: a randomized controlled study. Intern Med 2017;56(2):175-9. Am J Clin Dermatol 2010;11(4):247-267. View abstract. Hum Exp Toxicol 2012;31(12):1295-1298. View abstract. The 1:1 of peony and licorice group can significantly reduced the ureteral smooth muscle tension and Christina Loosestrife herb can increase the u reteral tension, but the amount is too large, the mechanism may be related with the diuretic row stone. mentioned adverse effects and recurrence rates. Korri, H., Awada, A., Baajour, W., Beaini, M., and Nasreddine, W. [Rapidly progressing quadriparesis secondary to licorice (souss) intoxication]. Peony (Paeonia spp). Liapina LA, Ammosova IaM, Novikov VS, et al. View abstract. View abstract. Inflammopharmacology 2022;30(2):477-486. View abstract. Licorice. It is used for stomach pain, abdominal pain and acute pain of gastrocnemius muscle contracture, etc. Chin J Integr Med 2022. In 1977, researchers reported the case of a 58-year-old woman who was eating a whopping 1.8 kilograms (about 63.5 ounces) of black licorice per week and went into cardiac arrest. The effect of dong quai on menopausal symptoms is unknown. Hyodo T, Taira T, Kumakura M, et al. In some cases, this might change the effects and side effects of a medication. They also have a range of other intriguing activities. View abstract. Strandberg TE, Jarvenpaa AL, Vanhanen H, McKeigue PM. It is often used together with peony, which can significantly enhance . 2011;25(1-2):21-38. Ann Clin Biochem 2007;44(Pt 4):397-399. . View abstract. Erratum in: Clin Rheumatol. Lee, S. M., Li, M. L., Tse, Y. C., Leung, S. C., Lee, M. M., Tsui, S. K., Fung, K. P., Lee, C. Y., and Waye, M. M. Paeoniae Radix, a Chinese herbal extract, inhibit hepatoma cells growth by inducing apoptosis in a p53 independent pathway. Chem Pharm Bull (Tokyo) 1994;42(5):1056-1062. View abstract. 1994;14:207-9, 195. . van den Bosch AE, van der Klooster JM, Zuidgeest DM, et al. Nabeshima, S., Kashiwagi, K., Ajisaka, K., Masui, S., Takeoka, H., Ikematsu, H., and Kashiwagi, S. A randomized, controlled trial comparing traditional herbal medicine and neuraminidase inhibitors in the treatment of seasonal influenza. View abstract. Pharm Biol 2021;59(1):1276-1285. Dehours E, Vall B, Roug-Bugat ME, Florent B, Bounes V, Franchitto N. Suspected hypokalaemia following liquorice ingestion on board ship. J Neuroophthalmol. Kwon S, Jin C, Cho SY, et al. Common side effects of licorice include: Absence of a menstrual period . Licorice, tobacco chewing, and hypertension. Licorice (Glycyrrhizae Radix) 15 g: NR: Zhao (2016) [36] . J Ethnopharmacol 2011;135(1):162-72. View abstract. 6. Front Psychiatry 2020;11:605949. View abstract. Exploring Pseudohyperaldosteronism in Glycyrrhizic Acid Toxicity From Chronic Licorice Root Consumption. J Clin Psychopharmacol 2016;36(6):572-9. Biol Pharm Bull 1998;21:1277-81. Strandberg TE, Andersson S, Jarvenpaa AL, et al. View abstract. Licorice might change how these pumps work and change how much medication stays in the body. Messier, C., Epifano, F., Genovese, S., and Grenier, D. Licorice and its potential beneficial effects in common oro-dental diseases. Select a condition to view a list of vitamins. Brayley J, Jones J. Life-threatening hypokalemia associated with excessive licorice ingestion (letter). J Altern Complement Med. View abstract. Cancer Res 2000;60:5704-9.. View abstract. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. View abstract. View abstract. Phytomedicine 2003;10:271-85. Fujisawa, Y., Sakamoto, M., Matsushita, M., Fujita, T., and Nishioka, K. Glycyrrhizin inhibits the lytic pathway of complement--possible mechanism of its anti-inflammatory effect on liver cells in viral hepatitis. Paeonia lactiflora Pall inhibits bladder cancer growth involving phosphorylation of Chk2 in vitro and in vivo. View abstract. View abstract. View abstract. Therapeutic basis of glycyrrhizin on chronic hepatitis B. Antiviral Res 1996;30:171-7. Z., Zhang, Y. Chinese herbal medicine for atopic eczema. Licorice has anti-acid and relieves the tension of gastrointestinal smooth muscle. Berlango Jimenez A., Jimenez Murillo L., Montero Perez F. J., Munoz Avila J. Tsuda T, Sugaya A, Ohguchi H, et al. J Ethnopharmacol 2002;81:101-4.. View abstract. Turpie AG, Runcie J, Thomson TJ. About Dr.Cope. View abstract. View abstract. N Engl J Med 1968;278(25):1381-1383. Rev Med Brux 2008;29(5):490-493. Evid Based Complement Alternat Med. This can be severe. Also for White Peony, the plant that is used in traditional . Int Immunopharmacol 2012;14(1):27-31. Arase, Y., Ikeda, K., Murashima, N., Chayama, K., Tsubota, A., Koida, I., Suzuki, Y., Saitoh, S., Kobayashi, M., and Kumada, H. The long term efficacy of glycyrrhizin in chronic hepatitis C patients. Little is known about whether it's safe to use licorice root while breastfeeding. . Guo, T. L. and Zhou, X. W. [Clinical observations on the treatment of the gestational hypertension syndrome with Angelica and Paeonia powder]. A comparison of carbenoxolone sodium and deglycyrrhizinated liquorice in the treatment of gastric ulcer in the ambulant patient. Ann Noninvasive Electrocardiol. Medicine (Baltimore) 2019;98(35):e16601. View abstract. van Rossum, T. G., Vulto, A. G., Hop, W. C., and Schalm, S. W. Pharmacokinetics of intravenous glycyrrhizin after single and multiple doses in patients with chronic hepatitis C infection. N Engl J Med. View abstract. Licorice, tobacco chewing, and hypertension. Taking peony root along with phenytoin might decrease the effects of phenytoin and increase the risk of seizures. Tooth decay. Hajiaghamohammadi, A. Scali, M., Pratesi, C., Zennaro, M. C., Zampollo, V., and Armanini, D. Pseudohyperaldosteronism from liquorice-containing laxatives. Liang, R. N., Liu, J., and Lu, J. Effects of glycyrrhizin on biochemical tests in patients with chronic hepatitis -- double blind trial. Wang W, Tian DD, Zheng B, et al. Mohire, N. C. and Yadav, A. V. Chitosan-based polyherbal toothpaste: as novel oral hygiene product. Gomaa AA, Mohamed HS, Abd-Ellatief RB, Gomaa MA, Hammam DS. Nutrition 2002;18(3):268-273. View abstract. Lin SH, Yang SS, Chau T, Halperin ML. Gupta D, Agrawal S, Sharma JP. Fiore, C., Eisenhut, M., Krausse, R., Ragazzi, E., Pellati, D., Armanini, D., and Bielenberg, J. Antiviral effects of Glycyrrhiza species. Bruynzeel DP. View abstract. Paeoniflorin, a constituent of white peony root, has demonstrated inhibition of testosterone synthesis in vitro, without affecting estradiol synthesis.It reduces testosterone production by the ovaries but not the adrenal glands. A specific type of peony product, total glucosides of peony (TGP), has most often been used by adults in doses of 600 mg by mouth three times daily for up to 24 weeks. J Pharmacobiodyn 1983;6:153-60. . 2020;16(3):458-462. Chin Med J (Engl.) View abstract. Armanini D, Bonanni G, Mattarello MJ, et al. View abstract. View abstract. Ito, M., Nakashima, H., Baba, M., Pauwels, R., De Clercq, E., Shigeta, S., and Yamamoto, N. Inhibitory effect of glycyrrhizin on the in vitro infectivity and cytopathic activity of the human immunodeficiency virus [HIV (HTLV- III/LAV)]. View abstract. View abstract. Mol.Nutr Food Res 2011;55(2):318-327. Zhongguo Zhong Xi Yi Jie He Za Zhi. Sato H, Goto W, Yamamura J, et al. Bisogni V, Rossi GP, Cal LA. Pharmacotherapeutic effects of toki-shakuyaku-san on leukorrhagia in young women. View abstract. Birth outcome in relation to licorice consumption during pregnancy. This fragrant, perennial plant -- a member of the celery family -- has smooth purplish stems and umbrella-shaped clusters of white flowers and winged fruits in July and August. View abstract. Licorice root and white poney is a common herbal formula for PCOS originating in traditional Chinese medicine.
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